Endocrine disruptors are known to cause harmful effects to human through various exposure routes. These chemicals mainly appear to interfere with the endocrine or hormone systems. As importantly, numerous studies have demonstrated that the accumulation of endocrine disruptors can induce fatal disorders including obesity and cancer. Using diverse biological tools, the potential molecular mechani...

INTRODUCTION Endocrine disruptors or environmental agents, disrupt the endocrine system, leading to various adverse effects in humans and animals. Although the phenomenon has been noted historically in the cases of diethylstilbestrol (DES) and dichlorodiphenyltrichloroethane (DDT), the term "endocrine disruptor" is relatively new. Endocrine disruptors can have a variety of hormonal activities s...

UNLABELLED BACKGROUNDS Previous studies suggested that endocrine disruptors (ED) are toxic on preimplantation embryos and inhibit development of embryos in vitro culture. However, information about the toxicity of endocrine disruptors on preimplantation development of embryo in human reproductive environment is lacking. METHODS Bisphenol A (BPA) and Aroclor 1254 (polychlorinated biphenyls)...

BACKGROUND Recent reports suggest that endocrine disruptors may leach into the contents of bottles made from polyethylene terephthalate (PET). PET is the main ingredient in most clear plastic containers used for beverages and condiments worldwide and has previously been generally assumed not to be a source of endocrine disruptors. OBJECTIVE I begin by considering evidence that bottles made fr...

The role of Endocrine Disruptors as real risk for ecosystems, wildlife and humans represents a concern and the debate on this issue is open owing the conflicting interests between the producers of these products and the scientific community. A concise overview of the nature, presence and adverse effects induced in wildlife and humans by Endocrine Disruptors is illustrated. Some indications to r...

The workshop "Characterizing the Effects of Endocrine Disruptors on Human Health at Environmental Exposure Levels" was held to provide a forum for discussions and recommendations of methods and data needed to improve risk assessments of endocrine disruptors. This article was produced by a working group charged with determining the basic mechanistic information that should be considered when des...

aims of the study: endometriosis is a prevalent gynecologic disorder in young women at reproductiveage but the underlying risk factors have not identified yet in iran and other neighboringcountries. persistent exposure to environmental endocrine disrupting chemicals (edcs) in particulardioxins, pahs and polychlorinated biphenyls (pcbs) with xenoestrogenic potentials have beenhypothesized in the...

to interfere with the endocrine system, so-called endocrine disruptors, both large-scale consortia funded by the European Union (EU). The meeting was attended by more than 170 scientists from academia, industry, government agencies, and other organizations. EDEN and FIRE were part of the CREDO cluster (Cluster for Research on Endocrine Disruption), an umbrella organization of more than 60 EU-fu...